Mathematical Modelling of Multidrug-Resistant Tuberculosis with Vaccination

Authors

Abstract

Tuberculosis (TB) infectious disease caused by Mycobacterium tuberculosis (Mtb) remains a health threat to the community. In particular, TB infections that are resistant to drugs or commonly known as MDR-TB are still experiencing difficulties, especially in the treatment process. Currently, the development of a vaccine against latent TB is essential in combating the TB epidemic. In this paper, a mathematical model for MDR-TB is developed to estimate the impact of vaccination on future epidemiology. The equilibrium point and stability analysis of the model are also determined and performed, respectively. Furthermore, numerical simulations were carried out using MATLAB software based on the data that had been obtained to predict the development of MDR-TB associated vaccination and consider relevant suggestions in the future.

Author Biographies

Sulasri Suddin, Universitas Timor

Education Mathematics Study Program

Elinora Naikteas Bano, Universitas Timor

Mathematics Study Program

Meri Hari Yanni, STKIP Bumi Persada Lhokseumawe

Informatics Study Program

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Published

15-12-2021

How to Cite

Suddin, S., Bano, E. N., & Yanni, M. H. (2021). Mathematical Modelling of Multidrug-Resistant Tuberculosis with Vaccination. MATEMATIKA, 109–120. Retrieved from https://matematika.utm.my/index.php/matematika/article/view/1318

Issue

Volume 37 (December 2021)

Section

Articles

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Copyright of articles that appear in MATEMATIKA: MJIAM belongs exclusively to Penerbit UTM Press, Universiti Teknologi Malaysia. This copyright covers the rights to reproduce the article, including reprints, electronic reproductions or any other reproductions of similar nature.